Caffeine, Multivitamins and Miscarriage Risk
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A new study from the National Institutes of Health and Ohio State University in Columbus reports that a woman is more likely to miscarry if she and her partner drink more than two caffeinated beverages a day during the weeks leading up to conception.
Similarly, women who drank more than two daily caffeinated beverages during the first seven weeks of pregnancy were also more likely to miscarry.
However, women who also took a daily multivitamin before conception and through early pregnancy were less likely to miscarry than women who did not.
Of the 344 pregnancies studied, 98 (28 percent) ended in miscarriage. For the preconception period, miscarriage was associated with a female age of 35 or above, for a hazard ratio of 1.96 (nearly twice the miscarriage risk of younger women).
Both male and female consumption of more than two caffeinated beverages a day also was associated with an increased hazard ratio: 1.74 for females and 1.73 for males.
Because their study found caffeine consumption before pregnancy was associated with a higher risk of miscarriage, it’s more likely that caffeinated beverage consumption during this time directly contributes to pregnancy loss.
On a positive note, the researchers saw a reduction in miscarriage risk for women who took a daily multivitamin. During the preconception period, researchers found a hazard ratio of 0.45 — a 55 percent reduction in risk for pregnancy loss. Women who continued to take the vitamins through early pregnancy had a hazard ratio of 0.21, or a risk reduction of 79 percent.